Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH.
Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with macrophages is a key event determining the outcome of infection.Urease is a major virulence factor in C.neoformans but its role during macrophage interaction has Bike Parts - Tires - 27.5" not been characterized.Consequently, we analyzed the effect of urease on