CRYPTOCOCCUS NEOFORMANS UREASE AFFECTS THE OUTCOME OF INTRACELLULAR PATHOGENESIS BY MODULATING PHAGOLYSOSOMAL PH.

Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH.

Cryptococcus neoformans is a facultative intracellular pathogen and its interaction with macrophages is a key event determining the outcome of infection.Urease is a major virulence factor in C.neoformans but its role during macrophage interaction has Bike Parts - Tires - 27.5" not been characterized.Consequently, we analyzed the effect of urease on

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Targeting the Sugary Armor of Klebsiella Species

The emergence of multidrug-resistant strains of Gram-negative Klebsiella species is an urgent global threat.The World Health Organization has listed Klebsiella pneumoniae as one of the global priority pathogens in critical need of next-generation antibiotics.Compared to other Gram-negative pathogens, K.pneumoniae accumulates a greater diversity of

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The values and principles underpinning community engagement approaches to tackling antimicrobial resistance (AMR)

This paper presents seven values underpinning the application of Community Engagement (CE) approaches to the One Health challenge of antimicrobial resistance (AMR) developed during an international workshop in June 2019.We define a value as a quality or standard which a CE project is aiming for, whilst a principle is an objective which underpins th

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